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The chemistry of the Kossel’s test for purine bases

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  • The chemistry of the Kossel’s test for purine bases

Sánchez-Viesca, Francisco * and Gómez, Reina

Organic Chemistry Department, Faculty of Chemistry, National Autonomous University of Mexico, Mexico City (CDMX), Mexico.

Review Article

Magna Scientia Advanced Research and Reviews, 2021, 01(02), 018-023
Article DOI: 10.30574/msarr.2021.1.2.0001
DOI url: https://doi.org/10.30574/msarr.2021.1.2.0001

Received on 02 January 2021; revised on 09 January 2021; accepted on 11 January 2021

Albrecht Kossel discovered the purine adenine and the pyrimidine thymine. He extended the murexide test for uric acid to adenine, guanine, hypoxanthine and xanthine. Since the structural differences in these compounds alter the pathways in these tests, we disclosed the reaction course in these assays. We provide the reaction sequence from the bi-annular base to the final product, the colored sodium purpurate.

Alloxan; Degradation; Oxidation; Purpuric acid; Reactive intermediates; Uramil

https://magnascientiapub.com/journals/msarr/node/76

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Sánchez-Viesca, Francisco , Gómez and Reina. The chemistry of the Kossel’s test for purine bases. Magna Scientia Advanced Research and Reviews, 2021, 01(02), 018-023. https://doi.org/10.30574/msarr.2021.1.2.0001

Copyright © 2021 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0

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