1 Institute of Malariology, Parasitology and Entomology Quy Nhon, Binh Dinh, Vietnam.
2 Oxford University Clinical Research Unit (OUCRU), Vietnam.
World Journal of Advanced Research and Reviews, 2020, 07(03), 241-245
Article DOI: 10.30574/wjarr.2020.7.3.0326
DOI url: https://doi.org/10.30574/wjarr.2020.7.3.0326
Received on 25 August 2020; revised on 24 September 2020; accepted on 26 September 2020
Estimating malaria parasite density is necessary for disease management, clinical trials and drug efficacy studies. This study was conducted to compare the malaria parasite density among patients using actual white blood cell (WBC) and the assumed WBC counts (8.0 ×109/l). A cross-sectional study was conducted in Dak Lak, Vietnam. WBC and asexual malaria parasite counts were performed on blood films. Eighty patients were enrolled. The mean (±SD) of WBCs was 5.84±1.63 ×109/l. The median (IQR) of parasite density using the assumed WBCs (8000 cells/µl) (11057.50 [2388.50-34210.75] rings/µl) was significantly higher than that estimation based on the actual WBC count (6898.61 [1892.12-24623.10] rings/µl) (p<0.001). Therefore, this study recommended the use of actual WBC count to estimate malaria parasite density in P. falciparum – infected patients in Dak Lak, Vietnam.
Malaria; Parasite density; Assumed white blood cell; Actual white blood cell
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Quang Hong Huynh, Khanh Van Chau, Hien Thanh Pham, Hien Tinh Tran, Nhien Thuy Thanh Nguyen and Hong Duc Nguyen. Malaria parasite density estimation using actual and assumed white blood cell counts in Plasmodium falciparum-infected patients in Dak Lak province, Vietnam. World Journal of Advanced Research and Reviews, 2020, 07(03), 241-245. https://doi.org/10.30574/wjarr.2020.7.3.0326
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